Clinical and Experimental Radiobiology Course
Clinical and Experimental Radiobiology is a five-day course that takes place at the University of Toronto in the Spring every year.
This program provides a comprehensive overview of radiation biology with a particular emphasis on aspects of direct relevance to the practice of radiation oncology. It addresses the molecular and cellular responses to radiation-induced damage that influence cell death in both tumors and normal tissues. Quantitation of radiation effects and the underlying biological basis for fractionation of radiotherapy and dose-response relationships in the clinic are covered in depth. The biological basis for current approaches to improve radiotherapy will be described including novel fractionation schemes, retreatment issues, targeting hypoxia, biological modifiers and combined radiotherapy/chemotherapy.
The suggested textbook for this course is Basic Clinical Radiobiology, Fifth Edition. It is strongly recommended that you read this book before attending the course.
Dates and Registration
Course date & time: April 25-29, 2022; time: TBA
The exam is only mandatory for students who require course credit. If you are taking this course for other reasons, the exam is optional.
Final exam date & time: May 6, 2022; time: TBA
Final exam location: TBA
Program Goals and Learning Objectives
- Apply novel forms of therapy, including combination therapy with chemotherapy and targeted agents to improve patient outcomes;
- Improve the safety of radiation therapy and reduce side effects through an understanding of the biological principles involved;
- Describe the key aspects of radiation biology that are of particular relevance to the practice of radiation oncology;
- Predict the molecular and cellular responses to radiation-induced damage that influence cell death in both tumors and normal tissues;
- Quantify the radiation effects and the underlying biological basis for fractionation of radiotherapy and dose-response relationships in the clinic;
- Evaluate the biological basis for side effects that limit safe doses of treatment and retreatment.
The course is designed primarily to address the needs of radiation oncology residents and physics residents who are in radiation oncology departments. In addition, the course will be valuable to new researchers in radiation biology and to radiation oncology fellows or practicing oncologists who recognize a lack of basic science or want to update their knowledge.
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