Brian Keller MSc, PhD, FCCPM
Assistant Professor
Contact Info
T: (416) 480-6100
Odette Cancer Centre - Sunnybrook Health Sciences Centre
2075 Bayview Avenue
Toronto, ON, M4N 3M5
Please contact Faculty Member for more information
BSc (Hons.), Physics, University of Waterloo
MSc, Radiation Physics, McGill University
PhD, Radiation Medicine/Medical Physics, University of Toronto
DABR, diplomate of the American Board of Radiology in therapeutic radiologic physics
FCCPM, Fellow of the Canadian College of Physicists in Medicine
Professional Memberships
Member, Canadian Organization of Medical Physicists (COMP)
Member, American Association of Physicists in Medicine (AAPM)
Member, International Radiation Physics Society (IRPS)
Acting Head of Physics, Sunnybrook Odette Cancer Centre
Assistant Professor, Department of Radiation Oncology, University of Toronto
Site-Leader, Physics Residency Training Program, Sunnybrook Odette Cancer Centre
Clinical Interests
Permanent Breast Seed Implant Brachytherapy, High Precision Radiation Therapy using Novel X-Ray Energies, SBRT, High Dose Rate Brachytherapy, Image guided brachytherapy


Research Synopsis

  • Absolute radiation dosimetry of millimeter size fields using MR spectroscopy
  • Characterization of millimeter size radiation fields using polymer films and digital microscopy
  • Intermediate energy x-rays for high precision small field radiation therapy
  • Gold nanoparticle radiosensitization
  • Assessing different radionuclides for permanent seed brachytherapy

Publications and Awards

View PubMed search of this faculty member's recent publications.

Recent Publications

Keller BM, Ravi A, Sankreacha R and Pignol JP. Permanent breast seed implant dosimetry quality assurance. Int. J. Radiat. Oncol. Biol. Phys. 83 (1), 84-92, 2012.

Keller BM, Pignol JP, Beachey DJ and Presutti J. Intermediate energy photons (1 MV) to improve dose gradient, conformality and homogeneity: potential benefits for small field intracranial radiosurgery. Med Phys 36(1), 33-39, 2009.

Keller BM, Peressotti C and Pignol JP. Optical Imaging analysis of microscopic radiation dose gradients in Gafchromic EBT film using a digital microscope. Med Phys 35(8), 3740 – 3747, 2008.

Keller BM, Pignol JP, Rakovitch E, Sankreacha R, O’Brien P. A radiation badge survey for family members living with patients treated with a Pd-103 permanent breast seed implant. Int J Radiat Oncol Biol, 70(1), 267-271, 2008.

Keller BM, Beachey D and Pignol JP. Experimental measurement of radiological penumbra associated with intermediate energy x-rays (1 MV) and small radiosurgery field sizes. Med Phys 34(10), 3996-4002, 2007.

Keller BM, Sankreacha R, Rakovitch E, O’Brien P, Pignol JP. A permanent breast seed implant as partial breast radiation therapy for early stage breast cancer patients: A comparison of Palladium-103 and Iodine-125 isotopes based on radiation safety considerations. Int. J. Radiation Oncology Biol. Phys. 62 (2), 358 – 365, 2005.

Pignol JP, Keller BM, Rakovitch E, Sankreacha R, Que, W. First report of a permanent breast Pd-103 seed implant as adjuvant radiation treatment for early stage breast cancer. Int. J. Radiation Oncology Biol. Phys. 64 (1), 176-181, 2006.

Holly R, Keller BM, Pignol JP, Lemaire C and Peemoeller H. Initial Investigation on the use of MR Spectroscopy and micro-MRI of Gafchromic EBT radiotherapy film. Med Phys 36 (11), 5341-5346, 2009.

Pignol & Keller. Electron and photon spread contributions to the radiological penumbra for small monoenergetic x-ray beams (< 2 MeV). J Applied Physics, 105, 102011(1) – 102011(5), 2009.

Pignol JP, Rakovitch E, Keller BM, Sankreacha R and Chartier C. Tolerance and acceptance results of a palladium-103 permanent breast seed implant phase I/II study. Int J Radiat Oncol Biol Phys 73(5), 1482-1488, 2009.

Ravi A, Caldwell C, Keller B and Pignol JP. Online Gamma-camera Imaging of 103Pd Seeds (OGIPS) for permanent breast seed implantation. Phys Med Biol 52, 5921-5932, 2007.

Furstoss C, Reniers B, Bertrand MJ, Poon E, Carrier JF, Keller BM, Pignol JP, Beaulieu L and Verhaegen F. Monte Carlo study of LDR seed dosimetry with an application in a clinical brachytherapy breast implant. Med Phys 36(5), 1848-1858, 2009.