Academic Rank

Associate Professor

Professional Qualifications

PhD, Nuclear Engineering and Radiological Sciences, University of Michigan

Appointments

Associate Professor, Department of Radiation Oncology, University of Toronto
Associate Professor, Department of Medical Biophysics, University of Toronto
Medical Physicist, Princess Margaret Hospital/University Health Network
Associate Professor, Institute of Medical Sciences, University of Toronto

Academic & Clinical Interests

• Deformable Image Registration
• Quantification and evaluation of organ motion and deformation
• Image-guided radiotherapy
• Multi-modality imaging for radiotherapy
• Finite Element Modeling and Analysis
• Quantitative assessment of treatment response

Current Research Projects

• Development of a novel deformable image registration technique to facilitate classification, targeting, and monitoring of tumour and normal tissue response using finite element modeling.

Selected Publications

See current publications list at PubMed.

Brock KK. Imaging and image-guided radiation therapy in liver cancer. Semin Radia Oncol 21(4): 247-255, 2011.

Al-Mayah A, Moseley J, Velec M and Brock K. Toward efficient biomechanical-based deformable image registration of lungs for image-guided radiotherapy. Phys Med Biol 56: 4701-4713, 2011.

Eccles CL, Dawson LA, Moseley JL, Brock KK. Interfraction liver shape variability and impact on gtv position during liver stereotactic radiotherapy using abdominal compression. Int J Radiat Oncol Biol Phys 80(3): 938-46, 2011.

Brierley JD, Dawson LA, Bayley A, Sampson E, Scott S, Moseley J, Craig T, Cummings BJ, Dinniwell R, Kim JJ, Ringash J, Wong R, Brock KK. Rectal motion in patients receiving preoperative radiotherapy for carcinoma of the rectum. Int J Radiat Oncol Biol Phys 80(1): 97-102, 2011.

Velec M, Mosely J, Eccles C, Craig T, Sharpe M, Dawson LA, Brock KK. Effect of breathing motion on radiotherapy dose accumulation in the abdomen using deformable registration. Int J Radiat Oncol Bio Phys 80(1): 265-272, 2011.

Al-Mayah A, Moseley J, Hunter S, Velec M, Chau L, Breen S, Brock K. Biomechanical-based image registration for head and neck radiation treatment. Phys Med Biol 55(21): 6491-6500, 2010.

Vlad RM, Kolios MC, Moseley JL, Czarnota CJ, Brock KK. Evaluating the extent of cell death in 3D high frequency ultrasound by registration with whole-mount tumor histopathology. Med Phys 37(8): 4288-4297, 2010.

McGrath DM, Vlad RM, Foltz WD, Brock KK. Technical note: fiducial markers for correlation of whole-specimen histopathology with MR imaging at 7 tesla. Med Phys 37(5): 2321-2328, 2010.

Brock KK on behalf of the Deformable Registration Accuracy Consortium. Results of a multi-institution deformable registration accuracy study (MIDRAS). Int J Radiat Oncol Biol Phys 76(2): 583-96, 2010.

Brock KK, Dawson LA. Adaptive management of liver cancer radiotherapy. Semin Radiat Oncol 20(2): 107-115, 2010.

Al-Mayah A, Moseley J, Brock KK,. ‘Contact surface and material nonlinearity modeling of human lungs.’ Phys.Med. Biol. 53: 305-17, 2008.

Wiltshire K, Brock K, Haider M, Zwahlen D,. Kong V, Chan E, Moseley J. Bayley A, Catton C, Chung P, Gospodarowicz M, Milosevic M, Kneebone A, Warde P, Ménard C. Anatomic Boundaries of the CTV (Prostate Bed) after Radical Prostatectomy. Int J Radiat Oncol Biol Phys, 69(4); 1090-9. 2007

Hensel JM, Ménard C, Chung PWM, Kirilova A, Moseley JL, Haider MA, Brock KK, ‘The Development of a Multi-organ Finite Element Based Prostate Deformation Model Enabling the Registration of Endorectal Coil Magnetic Resonance Images (ERC-MRI) for Radiotherapy Planning’, Int J Radiat Oncol Biol Phys, Aug 1; 68(5): 1522-8, 2007.

Kaus MR, Brock KK, Pekar V, Bzdusek K, Jaffray DA, Assessment of a Model-Based Deformable Image Registration Approach for Radiotherapy Planning, Int. J. Radiat. Oncol. Biol. Phys, Jun 1;68(2): 572-80, 2007.

Nichol AM, Brock KK, Lockwood GA, Moseley DJ, Rosewall T, Warde PR, Catton CN, Jaffray DA. A Magnetic Resonance Imaging Study of Prostate Deformation Relative to Implanted Gold Fiducial Markers. Int J Radiat Oncol Biol Phys, 67(1): 48-56, 2006.

Voroney JP, Brock KK, Eccles C, Haider M, Dawson LA. Prospective Comparison of CT and MR for Liver Cancer Delineation Using Deformable Image Registration. Int J Radiat Oncol Biol Phys, 66(3): 780-91, 2006.

Hawkins M, Brock KK, Eccles, C, Moseley D, Jaffray DA, Dawson LA. Assessment of Residual Error in Liver Position using kV Cone-Beam CT for Liver Cancer High Precision Radiation Therapy Int J Radiat Oncol Biol Phys, Oct 1; 66(2): 610-9, 2006.

Brock KK, Dawson LA, Sharpe MB, Jaffray DA. Application of a Novel Deformable Image Registration Technique to Facilitate Classification, Tracking and Targeting of Tumor and Normal Tissue. Int J Radiat Oncol Biol Phys, 64(4): 1245-54, 2006.

Eccles C, Brock KK, Bissonnette JP, Hawkins M, Dawson LA. Reproducibility of liver position using active breathing coordinator for liver cancer radiotherapy. Int J Radiat Oncol Biol Phys, 64(3): 751-9, 2005.

Brock KK, Sharpe MB, Dawson LA, Kim SM, Jaffray DA, Accuracy of Finite Element Model (FEM)-based multi-organ deformable image registration. Med. Phys., 32(6):1647-59, 2005.